Seven children were among the dead in the strikes, says Syrian Observatory for Human Rights
Separate suspected Russian and US-led coalition strikes on Syria's Deir Ezzor province killed at least 39 civilians on Thursday, the Syrian Observatory for Human Rights monitor said.
The strikes hit several parts of the eastern province, where parallel Russian and US-backed ground offensives are under way against the Islamic State group.
The Britain-based monitor said seven children were among the dead in the strikes, which hit multiple parts of the province including the city of Mayadeen, a remaining IS stronghold.
Pressure continues on Deir Ezzor
The strikes come as Syria's army battles to oust IS from the provincial capital Deir Ezzor city, after breaking the militant group's two-year siege of government-held parts of the metropolis.
Backed by Russian air strikes, the army and allied fighters now hold over half the city, and are working to surround IS militants in the remaining parts.
On Thursday, the Observatory said the army seized the northern suburb of Al-Boghaliya, advancing to the adjacent western bank of the Euphrates river that slices diagonally across Deir Ezzor province.
They are still battling to take additional territory in the southern part of the city in order to encircle IS fighters.
On the opposite side of the river, the US-backed Syrian Democratic Forces, an alliance of Syrian Kurdish and Arab fighters, is also battling IS.
US-led and Russian strikes in support of the separate campaigns have killed dozens of civilians in recent days, including some fleeing the fighting and seeking shelter in tents along the banks of the Euphrates, according to the Observatory.
More than 330,000 people have been killed in Syria since the conflict began in March 2011 with anti-government protests before spiralling into a bloody civil war.